Nitrazepam is a benzodiazepine that is issued for treating a variety of sleep problems, such as insomnia. Being a Benzodiazepine, this medication works by relaxing the body and mind. It is a potent hypnotic medication that produces several effects including sedative, anxiolytic, amnestic, anticonvulsant, as well as skeletal muscle relaxing effects. Nitrazepam reduces the amount of time it takes to drift off to sleep and increases the amount of time it takes to stay asleep. This medication is also effective in the treatment of myoclonic seizures. It takes half an hour to take effect and induces sleep by about 6 to 8 hours on average.
Nitrazepam Mechanism of Action
Nitrazepam is a medication that belongs to a class of medications known as benzodiazepines. The medication affects the GABA receptors. As a result, there is increased GABA activity. GABA is the chief neurotransmitter in the brain that induces feelings of calm, a reduction in anxiety, and an overall depression of the nervous system by blocking the communication of chemical messages. The medication enhances this action by binding to its receptors.
Nitrazepam Dosage
Dosage is typically tailored to each individual’s requirements. If possible, the medication is recommended to be used on an occasional basis. Taking the medication over an extended period of time is not recommended.
You should take this medicine for as short a time as possible, and the lowest effective dosage must be used to begin treatment. It is important not to exceed your recommended dosage. The length of treatment with this medication generally ranges from 11 to 14 days. The maximum period for taking nitrazepam is four weeks.
Adults can take 5 mg of the medicine, 30 minutes before bedtime to help with sleep difficulties. This dosage can be increased to 10 mg if it is necessary. Children below the age of twelve should not use this medication. The recommended dosage for patients older than 65 years of age is 2.5 to 5 mg, before going to bed.
How to Take Nitrazepam
Nitrazepam is available in two forms: as an oral solution and as tablets. The most common way people take sleeping tablets UK is in tablet form. This may be done by simply putting the pill on your tongue and drinking a glass of water thereafter. When taking the pill, you must make sure that you do not put the pill too far back in your mouth because it can cause a gag reflex.
Among other usages instructions are:
- Chewing, crushing, or sucking on the tablet should not be done because this can affect the way the medicine works and can also cause a bitter aftertaste.
- To take the medication, only water should be used. No other beverages, such as alcoholic or sugary drinks, should be used.
- The suggested time for taking this medicine is shortly before you go to bed (60 minutes before bedtime).
For more information on how to take the medicine, you need to make sure that you read the patient information leaflet, which comes with the medication, carefully.
Nitrazepam Side Effects
Using benzodiazepines can cause certain side effects. Everyone reacts to the medication differently, so there is a possibility that you may not get the side effects at all. However, some adverse effects are more common than others. Below is a list of the most frequently seen adverse effects of nitrazepam:
- Dizziness
- Unsteadiness
- Fatigue
- Sedation
- Diarrhea
- Drowsiness
- Vomiting
- Nausea
These adverse effects do not need medical treatment and will subside as your body becomes used to the medication. However, if you have any significant or unusual side effects, you should seek medical assistance as soon as possible.
How Long Nitrazepam Last
The length of time a medicine remains in your system is dependent on you and the sort of medication you are taking in combination with nitrazepam. A typical dose of this medication lasts 6 to 8 hours in your system. Factors such as your age, gender, and the dose you are taking all have an impact on how long the medicine remains effective in your system.
In the case of nitrazepam brand name medication versus the generic option, the durational effects of both the medications will be the same. This is because both of these medications contain the same active ingredient and will thus, the medication will be active in the body for the same length of time. The duration of effectiveness of this sleep medicine will be specified in the information booklet that comes with your medication. Therefore, be sure to look at the leaflet for more information.
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