Natriuretic Peptides: What They Measure and How to Interpret Results
NT-proB-type Natriuretic Peptide (BNP) blood test
When your heart stops working normally, or when it can’t pump enough blood (congestive heart failure), the pressure in your blood vessels decreases. This causes B-type natriuretic peptide (BNP) levels to go down. N-terminal (NT)-pro hormone BNP (NT-proBNP) is a non-active prohormone that is released from the same molecule that produces BNP. Both BNP and NT-proBNP are released in response to changes in pressure inside the heart. These changes can be related to heart failure and other cardiac problems. Levels goes up when heart failure develops or gets worse, and levels go down when heart failure is stable. In most cases, BNP and NT-proBNP levels are higher in patients with heart failure than in people who have normal heart function
How is my level of BNP/NT-proBNP measured?
The BNP test measures the measurement of heart failure. It helps detect problems that may cause heart damage, such as chest pain and shortness of breath. A mechanical device called a sphygmomanometer is used to take the average of your blood pressure over five minutes. Blood samples are collected from your arm and then sent to the lab where doctors conduct various tests before getting a BNP or NT-proBNP result.
What do the results mean?
NEP is the most current method to evaluate and monitor heart failure. NEP is tested in patients with heart failure, low cardiac output syndrome and/or pulmonary oedema who are unable to clear their lungs due to poor left ventricular contractility or left ventricular dysfunction. The results help your doctor or nurse determine if you have heart failure, if worsening fatigue or shortness of breath is due to heart failure or another problem or if heart failure has progressed toward end-of-life. Based on your results, your doctor can choose the best treatment plan for you.
NT-proBNP is a useful indicator of fluid balance in chronic heart failure patients. A normal level of NT-proBNP, based on Cleveland Clinic’s Reference Range is:
- Less than 125 pg/mL for patients aged 0-74 years
- Less than 450 pg/mL for patients aged 75-99 years
If you have heart failure, the following NT-proBNP levels could mean your heart function is unstable. Your doctor may give you more information about how and when to test.
- Higher than 450 pg/mL for patients under age 50
- Higher than 900 pg/mL for patients age 50 and older
Your heart is a pump that helps circulate oxygen throughout your body. Your doctor or nurse can give you more specific information about your test results. Depending on your personal health history, your normal range may differ from other patients with different backgrounds.
BioLab B-type natriuretic peptide (BNP) therapeutic is a medication used to reduce or relieve the symptoms of congestive heart failure. This product is designed to help the body maintain normal blood pressure by controlling fluid and electrolyte retention, as well as increasing the volume and rate of urine production.
B-type natriuretic peptide (BNP) is released by the heart during heart failure and acts locally as a natriuretic peptide hormone. It has been used to guide the treatment of patients with chronic heart failure. The use of plasma levels of BNP in patients with chronic HF has been investigated in a number of randomised controlled trials (RCTs). However, the benefits of this treatment approach have been uncertain. We, therefore, performed a meta-analysis to examine the overall effect of BNP-guided drug therapy on cardiovascular outcomes in patients with chronic HF.
NT-proB-type Natriuretic Peptide (BNP) blood test
When your heart stops working normally, or when it can’t pump enough blood (congestive heart failure), the pressure in your blood vessels decreases. This causes B-type natriuretic peptide (BNP) levels to go down. N-terminal (NT)-pro hormone BNP (NT-proBNP) is a non-active prohormone that is released from the same molecule that produces BNP. Both BNP and NT-proBNP are released in response to changes in pressure inside the heart. These changes can be related to heart failure and other cardiac problems. Levels goes up when heart failure develops or gets worse, and levels go down when heart failure is stable. In most cases, BNP and NT-proBNP levels are higher in patients with heart failure than in people who have normal heart function
How is my level of BNP/NT-proBNP measured?
The BNP test measures the measurement of heart failure. It helps detect problems that may cause heart damage, such as chest pain and shortness of breath. A mechanical device called a sphygmomanometer is used to take the average of your blood pressure over five minutes. Blood samples are collected from your arm and then sent to the lab where doctors conduct various tests before getting a BNP or NT-proBNP result.
What do the results mean?
NEP is the most current method to evaluate and monitor heart failure. NEP is tested in patients with heart failure, low cardiac output syndrome and/or pulmonary oedema who are unable to clear their lungs due to poor left ventricular contractility or left ventricular dysfunction. The results help your doctor or nurse determine if you have heart failure, if worsening fatigue or shortness of breath is due to heart failure or another problem or if heart failure has progressed toward end-of-life. Based on your results, your doctor can choose the best treatment plan for you.
NT-proBNP is a useful indicator of fluid balance in chronic heart failure patients. A normal level of NT-proBNP, based on Cleveland Clinic’s Reference Range is:
- Less than 125 pg/mL for patients aged 0-74 years
- Less than 450 pg/mL for patients aged 75-99 years
If you have heart failure, the following NT-proBNP levels could mean your heart function is unstable. Your doctor may give you more information about how and when to test.
- Higher than 450 pg/mL for patients under age 50
- Higher than 900 pg/mL for patients age 50 and older
Your heart is a pump that helps circulate oxygen throughout your body. Your doctor or nurse can give you more specific information about your test results. Depending on your personal health history, your normal range may differ from other patients with different backgrounds.
BioLab B-type natriuretic peptide (BNP) therapeutic is a medication used to reduce or relieve the symptoms of congestive heart failure. This product is designed to help the body maintain normal blood pressure by controlling fluid and electrolyte retention, as well as increasing the volume and rate of urine production.
B-type natriuretic peptide (BNP) is released by the heart during heart failure and acts locally as a natriuretic peptide hormone. It has been used to guide the treatment of patients with chronic heart failure. The use of plasma levels of BNP in patients with chronic HF has been investigated in a number of randomised controlled trials (RCTs). However, the benefits of this treatment approach have been uncertain. We, therefore, performed a meta-analysis to examine the overall effect of BNP-guided drug therapy on cardiovascular outcomes in patients with chronic HF.